N6-BENZYLADENOSINE

  • Name: N6-BENZYLADENOSINE
  • CAS: 4294-16-0
  • Purity: 99%
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Details

N6-BENZYLADENOSINE GMP Manufacturer Global Trade 4294-16-0 with Fast Delivery

  • Molecular Formula: C17H19N5O4
  • Molecular Weight: 357.369
  • Appearance/Colour: white solid 
  • Vapor Pressure: 6E-20mmHg at 25°C 
  • Melting Point: 184-186 °C 
  • Refractive Index: 1.762 
  • Boiling Point: 689.3 °C at 760 mmHg 
  • PKA: 13.12±0.70(Predicted) 
  • Flash Point: 370.7 °C 
  • PSA： 125.55000 
  • Density: 1.62 g/cm3 
  • LogP: 0.12290 

N6-BENZYLADENOSINE(Cas 4294-16-0) Usage

Purification Methods

Purify it by recrystallisation from EtOH. It has max 266nm (aqueous EtOH/HCl) and 269 nm (aqueous EtOH/NaOH). [Kissman & Weiss J Org Chem 21 1053 1956, Beilstein 26 III/IV 3682.]

InChI:InChI=1/C17H19N5O4/c23-7-11-13(24)14(25)17(26-11)22-9-21-12-15(19-8-20-16(12)22)18-6-10-4-2-1-3-5-10/h1-5,8-9,11,13-14,17,23-25H,6-7H2,(H,18,19,20)

4294-16-0 Relevant articles

Anion exchange resins in phosphate form as versatile carriers for the reactions catalyzed by nucleoside phosphorylases

Artsemyeva, Julia N.,Buravskaya, Tatiana N.,Esipov, Roman S.,Konstantinova, Irina D.,Litvinko, Natalia M.,Mikhailopulo, Igor A.,Miroshnikov, Anatoly I.,Remeeva, Ekaterina A.

supporting information, p. 2607 - 2622 (2020/11/26)

In the present work, we suggested anion ...

NMR for screening and a biochemical assay: Identification of new FPPS inhibitors exerting anticancer activity

Grimaldi, Manuela,Randino, Rosario,Ciaglia, Elena,Scrima, Mario,Buonocore, Michela,Stillitano, Ilaria,Abate, Mario,Covelli, Verdiana,Tosco, Alessandra,Gazzerro, Patrizia,Bifulco, Maurizio,Rodriquez, Manuela,D'Ursi, Anna Maria

supporting information, (2020/02/15)

Farnesyl pyrophosphate synthase (FPPS) i...

NUCLEOSIDE AND NUCLEOTIDE ANALOGUES AS CD73 INHIBITORS AND THERAPEUTIC USES THEREOF

-

Page/Page column 29, (2018/12/02)

Nucleoside and nucleotide compounds and ...

N6-isopentenyladenosine a new potential anti-angiogenic compound that targets human microvascular endothelial cells in vitro

Castiglioni, Sara,Romeo, Valentina,Casati, Silvana,Ottria, Roberta,Perrotta, Cristiana,Ciuffreda, Pierangela,Maier, Jeanette A. M.

, p. 533 - 545 (2018/12/04)

N6-isopentenyladenosine is an anti-proli...

4294-16-0 Process route

6-benzylaminopurine
1214-39-7,3458-19-3

6-benzylaminopurine

G
118-00-3

G

N<sub>6</sub>-Benzyladenosine
4294-16-0

N6 -Benzyladenosine

Conditions
Conditions Yield
With recombinant E. coli purine nucleoside phosphorylase; In aq. phosphate buffer; at 40 ℃; for 26h; pH=7.0;
67%
1-N-benzyl-N<SUP>6</SUP>-acetyl-2',3',5'-tri-O-acetyladenosine

1-N-benzyl-N6 -acetyl-2',3',5'-tri-O-acetyladenosine

N<sub>6</sub>-Benzyladenosine
4294-16-0

N6 -Benzyladenosine

Conditions
Conditions Yield
1-N-benzyl-N6-acetyl-2',3',5'-tri-O-acetyladenosine; With ammonia; In methanol; at 20 ℃; for 120h;
With ammonium hydroxide; at 20 ℃; for 168h;
32%

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