2-METHYL-2-PHENYL-INDAN-1-ONE
- Name: 2-METHYL-2-PHENYL-INDAN-1-ONE
- CAS: 10474-32-5
- Purity: 99%
Details
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- Molecular Formula: C16H14O
- Molecular Weight: 222.287
- Vapor Pressure: 0.00012mmHg at 25°C
- Boiling Point: 335.4°Cat760mmHg
- Flash Point: 143.3°C
- PSA： 17.07000
- Density: 1.124g/cm3
- LogP: 3.38330
2-METHYL-2-PHENYL-INDAN-1-ONE(Cas 10474-32-5) Usage
|
General Description |
2-Methyl-2-phenyl-indan-1-one is a chemical compound with the molecular formula C15H14O. It is a white crystalline solid that is commonly used in the production of fragrances and as a flavoring agent. 2-METHYL-2-PHENYL-INDAN-1-ONE has a strong and sweet floral odor, making it a popular ingredient in various cosmetic and personal care products. It is also used in the manufacturing of perfumes, soaps, and other scented products. Additionally, 2-methyl-2-phenyl-indan-1-one has been studied for its potential pharmaceutical and medicinal applications, including its use as an anti-inflammatory and anti-fibrotic agent. |
InChI:InChI=1/C16H14O/c1-16(13-8-3-2-4-9-13)11-12-7-5-6-10-14(12)15(16)17/h2-10H,11H2,1H3
10474-32-5 Relevant articles
Diboron-Promoted Reduction of Ni(II) Salts: Precatalyst Activation Studies Relevant to Ni-Catalyzed Borylation Reactions
Joannou, Matthew V.,Sarjeant, Amy A.,Wisniewski, Steven R.
, p. 2691 - 2700 (2021/08/20)
The activation and reduction of nickel(I...
Enantioselective Intramolecular Hydroacylation of Unactivated Alkenes: An NHC-Catalyzed Robust and Versatile Formation of Cyclic Chiral Ketones
Janssen-Müller, Daniel,Schedler, Michael,Fleige, Mirco,Daniliuc, Constantin G.,Glorius, Frank
supporting information, p. 12492 - 12496 (2015/10/12)
A highly enantioselective intramolecular...
Nickel-catalyzed enantioselective C-C bond formation through C sp 2 -O cleavage in aryl esters
Cornella, Josep,Jackson, Evan P.,Martin, Ruben
supporting information, p. 4075 - 4078 (2015/03/30)
We report the first enantioselective C-C...
Enantioselective α-arylation of cyclic ketones catalyzed by a combination of an unmodified Cinchona alkaloid and a palladium complex
Richter, Christian,Ranganath, Kalluri V. S.,Glorius, Frank
supporting information; experimental part, p. 377 - 382 (2012/04/11)
A palladium/Cinchona alkaloid-catalyzed ...
10474-32-5 Process route
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-
17496-14-9
2,3-dihydro-2-methyl-1H-inden-1-one
-
-
108-90-7
chlorobenzene
-
-
1005420-27-8,10474-32-5,887255-49-4
(±)-2-methyl-2-phenyl-2,3-dihydro-1H-inden-1-one
| Conditions | Yield |
|---|---|
|
With
tetrahydroxydiboron; trans-[NiIICl2(H2O)4]·2H2O; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; N-ethyl-N,N-diisopropylamine; cyclo-octa-1,5-diene; sodium t-butanolate;
In
methanol; toluene;
at 60 ℃;
for 24h;
Reagent/catalyst;
Glovebox;
Inert atmosphere;
Sealed tube;
|
99%
|
|
With
bis(1,5-cyclooctadiene)nickel (0); (R)-2,2'-bis(diphenylphosphanyl)-1,1'-binaphthyl; sodium t-butanolate;
In
toluene;
at 60 ℃;
for 36h;
optical yield given as %ee;
enantioselective reaction;
Inert atmosphere;
|
80%
|
-
-
1325230-39-4
2-(2-phenylallyl)benzaldehyde
-
-
1005420-27-8,10474-32-5,887255-49-4
(±)-2-methyl-2-phenyl-2,3-dihydro-1H-inden-1-one
| Conditions | Yield |
|---|---|
|
With
3-(2,4,6-trimethyl-phenyl)-5,6,7,8-tetrahydro-4H-cycloheptathiazol-3-ium perchlorate; 1,8-diazabicyclo[5.4.0]undec-7-ene;
In
1,4-dioxane;
at 120 ℃;
for 2h;
Inert atmosphere;
|
91%
|
10474-32-5 Upstream products
-
201230-82-2
carbon monoxide
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5814-85-7
1,2-diphenylpropane
-
16619-12-8
2-phenyl-indan-1-one
-
74-88-4
methyl iodide
10474-32-5 Downstream products
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104049-21-0
5-Isopropyl-2-methyl-2-phenyl-indan-1-one
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104049-28-7
1-Isopropyl-2-methyl-2-phenyl-indan-1-ol
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103376-55-2
(1R,2R)-2-Methyl-2-phenyl-1-prop-1-ynyl-indan-1-ol
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103376-55-2
(1S,2R)-2-Methyl-2-phenyl-1-prop-1-ynyl-indan-1-ol
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